Clomid yog dab tsi?

Clomid cov qauv tshuaj yog ua raws li triphenylethylene derivatives, uas muab nws lub peev xwm los sib tw khi rau cov tshuaj estrogen receptors. Qhov kev txiav txim no txwv tsis pub cov tshuaj estrogen los ntawm kev tawm dag zog nws cov lus pom tsis zoo ib txwm ua rau ntawm hypothalamus thiab pituitary caj pas. Yog li ntawd, lub caj pas pituitary tso tawm ntau lub follicle-stimulating hormone (FSH) thiab luteinizing hormone (LH), uas yog qhov tseem ceeb rau kev loj hlob ntawm follicular thiab ovulation.

Clomid ua haujlwm los ntawm kev teeb tsa cov tshuaj tiv thaiv kab mob los tsim cov tshuaj hormones hauv koj lub cev. Thaum koj noj Clomid, nws mus rau cov receptors hauv koj lub hlwb uas khi nrog estrogen. Qhov no ua rau koj lub cev xav tias koj cov tshuaj estrogen tsawg dhau, thiab kom them nyiaj, nws tsim ntau cov tshuaj follicle-stimulating hormone (FSH).

FSH tuaj yeem txhawb cov tshuaj estrogen, tab sis qhov tseem ceeb tshaj, nws tseem yog lub luag haujlwm rau kev txhawb nqa koj lub zes qe menyuam follicles. Koj cov follicles ntawm zes qe menyuam tuav koj cov qe tsis paub tab, yog li thaum cov follicles txhawb nqa, lawv tuaj yeem loj hlob cov qe rau hauv cov laus uas npaj txhij rau fertilization.

Feem ntau, cov kws kho mob yuav xav txog kev sau tshuaj Clomid thaum koj tsis tuaj yeem xeeb tub tom qab ib xyoos ntawm kev sim - thiab muaj peev xwm luv li rau lub hlis yog tias koj muaj hnub nyoog tshaj 35 xyoos. Yog tias koj tau raug soj ntsuam thiab muab qhov kev kuaj mob ntawm "tsis muaj ntxiv lawm tshob." , "Clomid yog thawj kauj ruam zoo vim nws tsis muaj kev cuam tshuam thiab pheej yig heev. Yog tias qhov no tshwm sim, koj txoj kev kho mob feem ntau yuav suav nrog insemination.

Uas tau hais tias, muaj qee lub sijhawm thaum Clomid tuaj yeem raug sau ua ntej. Clomid kuj tseem tuaj yeem pab cov xwm txheej zoo li polycystic zes qe menyuam syndrome (PCOS) lossis kev coj khaub ncaws tsis tu ncua uas tiv thaiv qhov tshwm sim ntawm ovulation. Letrozole yog lwm hom tshuaj uas tuaj yeem siv rau hauv qhov chaw no.

Clomid tsis tau sau tseg rau cov poj niam uas tau dhau los ntawm cov poj niam cev xeeb tub thiab tsis muaj cov qe siv tau ntxiv lawm.

Koj tus kws kho mob yuav qhia koj kom noj Clomid thaum pib koj lub cev xeeb tub, feem ntau ntawm hnub 3 thiab 5. Koj yuav tau noj ib ntsiav tshuaj ib hnub rau tsib hnub. Tom qab ntawd, koj yuav ua lub neej zoo li qub kom txog thaum koj lub voj voog tom ntej yuav pib. Yog tias koj tseem tsis tau xeeb tub, koj tus kws kho mob yuav pom zoo rau lwm yam kev kho mob Clomid. Feem ntau, koj tus kws kho mob yuav tsis pom zoo ntau tshaj li rau 6 chav kawm ntawm Clomid, zoo li nws tsis tau ua haujlwm los ntawm qhov ntawd, yuav muaj lwm qhov teeb meem fertility ntawm kev ua si.

Clomid tuaj yeem muaj qee qhov kev mob tshwm sim, suav nrog:

Cov kev mob tshwm sim hnyav dua ntawm Clomid tuaj yeem suav nrog qhov txawv txav ntawm qhov chaw mos los ntshav, hloov mus rau lub siab, thiab kev pom kev hloov pauv. Tham nrog koj tus kws kho mob tam sim ntawd yog tias koj tab tom ntsib ib qho ntawm cov no.

Ib qho kev pheej hmoo ntawm kev noj Clomid yog qhov muaj feem ntau ntawm kev tsim cov zes qe menyuam hyperstimulation syndrome (OHSS). OHSS ua rau cov kua dej nyob hauv plawv, hauv siab, thiab plab, uas tuaj yeem tsim nyog rau kev kho mob ntxiv. Txawm li cas los xij, qhov no tsuas yog tshwm sim hauv 0.5% ntawm txhua tus neeg noj Clomid.

Muaj ob peb yam uas yuav tsum zam thaum noj Clomid. Vim tias nws tuaj yeem ua rau kiv taub hau lossis pom kev hloov pauv, koj yuav xav kom tsis txhob haus cawv thiab tshuaj maj, vim tias cov no tuaj yeem ua rau cov tsos mob hnyav dua. Koj tseem yuav xav kom tsis txhob tsav tsheb lossis ua haujlwm tshuab kom txog thaum koj paub tias Clomid cuam tshuam rau koj li cas.

Koj yuav paub tias Clomid ua haujlwm yog tias koj muaj koj lub sijhawm 27-30 hnub tom qab noj tshuaj. Txawm li cas los xij, kom paub tseeb, koj tus kws kho mob yuav pom zoo kom ntshav ua haujlwm los ntsuas koj cov tshuaj hormones. Lawv kuj tseem pom zoo kom noj koj qhov ntsuas kub txhua tag kis kom pom tias koj tuaj yeem taug qab thaum ovulation tshwm sim.

Thaum koj ovulate ntawm Clomid yuav txawv ntawm ib tus neeg mus rau lwm tus. Qhov nruab nrab, feem ntau yuav ovulate ntawm 5 mus rau 10 hnub tom qab lawv noj lawv cov tshuaj Clomid kawg. Txawm li cas los xij, nws tseem ceeb heev uas yuav tsum nco ntsoov tias qee tus poj niam yuav ovulate ntau tom qab - txawm tias lig li 14 mus rau 21 hnub (2 mus rau 3 lub lis piam) tom qab Clomid (clomiphene) ntsiav tshuaj kawg.

Ob peb lub tswv yim rau kev xeeb tub ntawm Clomid yog kev sib deev thaum koj muaj hnub nyoog tshaj plaws thiab ua neej nyob noj qab haus huv. Koj tuaj yeem ntsuas koj qhov ntsuas kub txhua hnub lossis tau txais cov khoom ntsuas ntsuas ovulation txhawm rau taug qab koj qhov fertility. Yog tias koj siv cov khoom siv kuaj, koj yuav xav kom muaj kev sib deev tsis muaj kev tiv thaiv hauv 24 teev tom qab pom qhov loj ntawm luteinizing hormone - cov tshuaj hormones tseem ceeb uas tswj ovulation.

Kev ua neej nyob noj qab nyob zoo txhais tau hais tias muab cawv ntau dhau thiab siv tshuaj lom neeg ua si, noj zaub mov zoo, qoj ib ce tsis tu ncua, thiab nyob twj ywm hydrated. Tsis tas li ntawd, ua kom koj cov kev ntxhov siab tsawg nrog kev coj ua kom nco qab.

Kwv yees li 60 mus rau 85% ntawm cov neeg uas noj Clomid tuaj yeem ovulate ib txwm muaj dua. Zuag qhia tag nrho, koj muaj li ntawm 4 mus rau 12% txoj hauv kev xeeb tub txhua lub caij coj khaub ncaws thaum nyob rau Clomid. Nov yog qhov ua tau zoo ntawm Clomid los ntawm lub hnub nyoog zoo li tag nrho cov kev kho mob (qhov kev vam meej yog txhais tias cev xeeb tub thiab xav tias koj thawj qhov laj thawj rau kev xeeb tub yog anovulation).

Nco ntsoov tias kev noj Clomid kuj ua rau koj muaj feem ntau ntawm cov menyuam yaus ib zaug. Tej zaum koj yuav muaj sijhawm 5-8% rau menyuam ntxaib thiab a<1% chance for triplets.

1. Poj niam Infertility: Clomid feem ntau yog siv los ntxias ovulation rau cov poj niam uas muaj teeb meem xeeb tub vim muaj teeb meem xws li polycystic zes qe menyuam syndrome (PCOS), kev coj khaub ncaws tsis xwm yeem, lossis tsis piav qhia ntxiv lawm.

2.Off-Label siv: Qee zaum, Clomid yuav raug sau npe tawm los kho cov txiv neej infertility, hypogonadism nyob rau hauv cov txiv neej, thiab qee zaus rau lwm yam kev kho mob uas tswj hormonal muaj txiaj ntsig.

Stimulation ntawm ovulation: Los ntawm kev txhawb nqa kev tso tawm ntawm FSH thiab LH, Clomid pab txhawb kev loj hlob thiab kev loj hlob ntawm zes qe menyuam follicles, txhawb ovulation.

Kev kho mob uas tsis yog-invasive: Muab piv rau cov kev kho mob fertility ntau dua xws li hauv vitro fertilization (IVF), Clomid yog qhov tsis cuam tshuam thiab tsis tshua kim, ua rau nws nyiam pib kho rau ntau khub niam txiv.

Zoo Tsim Kev Nyab Xeeb Profile: Clomid tau siv ntau xyoo lawm thiab muaj kev ruaj ntseg profile zoo thaum siv kom tsim nyog raws li kev saib xyuas kev kho mob.

Clomid feem ntau yog siv los ntawm qhov ncauj, feem ntau pib ntawm qhov koob tshuaj qis ntawm 50 mg ib hnub rau tsib hnub, pib hnub thib 3, 4, lossis 5 hnub ntawm kev coj khaub ncaws. Cov koob tshuaj yuav raug hloov kho los ntawm tus kws kho mob raws li cov lus teb ntawm tus kheej, nrog rau kev kho mob feem ntau txwv rau rau qhov kev sim vim qhov txo qis kev ua tau zoo thiab muaj peev xwm cuam tshuam nrog kev siv ntev.

Kev nqus: Clomid yog nqus tau zoo ntawm qhov ncauj, nrog rau qhov siab tshaj plaws plasma concentrations tshwm sim li ntawm 6 mus rau 12 teev tom qab kev tswj hwm.

Metabolism: Nws ua rau cov metabolism hauv hepatic ntau dhau los ntawm cytochrome P450 enzymes, feem ntau CYP2D6 thiab CYP3A4, rau hauv cov metabolites tsis ua haujlwm.

Ib nrab neej: Kev tshem tawm ib nrab-lub neej ntawm Clomid yog li ntawm 5 mus rau 7 hnub, txhais tau tias nws tseem nyob hauv lub cev rau lub sijhawm ntev tom qab noj.

Kev tso tawm: Cov metabolites ntawm Clomid raug tshem tawm feem ntau hauv cov quav, nrog me me tawm hauv cov zis.

Ntau qhov kev tshawb fawb soj ntsuam tau pom tias Clomid qhov ua tau zoo hauv kev ua kom ovulation hauv cov poj niam uas muaj menyuam tsis taus. Cov txiaj ntsig tau zoo sib txawv raws li qhov ua rau muaj menyuam tsis taus, nrog kwv yees li 70% ntawm cov poj niam ovulating thiab txog 30% ua tiav cev xeeb tub tom qab ib lub voj voog kho. Cov txiaj ntsig kev vam meej tuaj yeem txhim kho nrog cov voj voog tom ntej, txawm hais tias qhov kev xeeb tub hauv plab yuav poob qis nrog kev siv ntev.

Hom	STADA
Cov npe lag luam	Clomiphene, Clomiphene, Clomid
CAS	911-45-5
Molar loj	405.966
Formula	C26H28ClNO
Purity	Tshaj 98%
Yam khoom	50mg * 50 Capsule

 

 

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Hauv cov ntsiab lus, Clomid yog cov tshuaj siv dav siv los kho cov poj niam tsis muaj menyuam los ntawm kev txhawb nqa ovulation los ntawm nws qhov kev ua ntawm estrogen receptors hauv hypothalamus thiab pituitary caj pas. Nws muaj cov kev kho mob uas tsis muaj kev cuam tshuam thiab pheej yig rau ntau tus khub niam txiv uas tawm tsam xeeb tub. Txawm hais tias feem ntau muaj kev nyab xeeb thiab siv tau zoo thaum siv raws li tau hais tseg, nws yog ib qho tseem ceeb rau cov kws kho mob saib xyuas cov neeg mob kom zoo rau cov kev mob tshwm sim thiab kho cov txheej txheem kho raws li qhov tsim nyog los txhim kho cov txiaj ntsig zoo thaum txo qis kev pheej hmoo.

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