SR9011 Sarms Bodybuilding CAS: 1379686-29-9

yog dab tsiTIAB SA 9011?

SR9011 yog ib qho kev sib xyaw ua ke uas yog ib qho tseem ceeb ntawm cov receptor nuclear REV - ERB agonist.

SARM yog ib chav kawm ntawm kev sim tshuaj sib txuas ua ke hu ua xaiv androgen receptor modulators. Nws yog qhov tseeb tias SR 9011 thiab SARM yog qhov sib txawv.

S 23 thiab RAD 140 yog SARMS loj, uas muaj zog heev thiab ze rau cov tshuaj anabolic steroids. SARM compounds xaiv khi rau androgen receptors hauv cov pob txha thiab cov leeg nqaij kom tswj cov leeg nqaij thiab pob txha noj qab haus huv.

Txawm hais tias SR 9011 thiab SARM tsis zoo ib yam, thaum bodybuilder siv SR 9011 rau bodybuilding, SR 9011 feem ntau yog cais raws li SARMs, qhov no yog vim SR 9011 bodybuilding plays lub luag hauj lwm zoo sib xws rau SARM rau bodybuilding.

Thaum feem ntau SARMs ua los ntawm kev khi rau androgen receptors nyob rau hauv lub cev nqaij daim tawv los yog pob txha cov ntaub so ntswg, SR 9011 ua los ntawm kev khi rau lub nuclear receptor REV - ERB nyob rau hauv lub hypothalamus, skeletal leeg, daim siab thiab adipose ntaub so ntswg. SR 9011 tsim cov kev hloov pauv ntawm qib cellular uas rov sau DNA qhia hauv ib txoj hauv kev tshwj xeeb. Los ntawm kev xa cov noob rau thiab tawm, SR 9011 cuam tshuam rau kev tsim cov piam thaj, cov roj cell loj hlob thiab tswj lub cev lub cev circadian rhythms. Qhov no yog tiag tiag SR 9011, uas yog dab tsi SR 9009 tau tsim rau.

SARM SR9011 Bodybuilding yog ib tug nuclear receptor REV - ERB agonist, yog li yog tias koj xav nkag siab tias SR 9011 ua haujlwm li cas, koj yuav tsum pib nrog lub nuclear receptor REV - ERB.

Qhov no intracellular receptor yog ib tug protein molecule nyob rau hauv lub nucleus. Lub nuclear receptor REV-ERB protein yog lub luag haujlwm rau ntau yam kev ua haujlwm hauv lub cev, suav nrog lub zog, carbohydrate thiab rog metabolism, uas nyob ntawm seb muaj pes tsawg tus receptor REV - ERB.

Peb paub tias kev siv zog ntawm cov txheej txheem physiological hloov nyob rau hauv ib hnub. Metabolism nrawm thaum nruab hnub thiab qeeb thaum hmo ntuj, mus txog qhov qis tshaj plaws thaum tsaus ntuj. Lub atherosclerosis ntawm kev ua haujlwm niaj hnub hu ua circadian atherosclerosis.

Lub moos tsiaj txhu tsiaj txhu yog tsim los ntawm lub moos tswv, nyob rau hauv Suprachiasmatic nucleus (SCN) ntawm lub hypothalamus, thiab lub moos peripheral, uas ua haujlwm ua pacemaker rau circadian rhythms thiab tswj cov cellular oscillators thoob plaws hauv lub cev los ntawm neural thiab hormonal signals. Lub moos roj ntsha peripheral tau muab faib rau ntau yam ntaub so ntswg thiab kabmob, xws li daim siab, lub raum, lub plawv thiab cov leeg, thiab muaj qee yam kev ywj pheej.

Circadian rhythms yog tswj los ntawm ntau lub tswv yim, nrog rau cov receptors nuclear. REV - ERB yog ib tug xws li regulator.

REV- ERB activation ua rau kev qhia ntawm cov noob encoding proteins ntawm enzymatic systems koom nrog hauv cov txheej txheem metabolic. Nyob rau hauv tej yam ntuj tso, REV - ERB kev ua si nce thaum nruab hnub thiab txo qis thaum hmo ntuj, raws li qhia los ntawm cov saum toj no basal metabolic tus nqi hloov.

SR 9011 yog ib tug nuclear receptor REV - ERB modulator. Raws li tus agonist rau qhov no receptor nuclear, SR 9011 txhawb nqa cov haujlwm ntawm cov noob uas cuam tshuam rau tus nqi ntawm cov txheej txheem metabolic. Txawm hais tias lub sijhawm nruab hnub, kev siv SR 9011 yog nrog los ntawm kev nce ntawm lub zog, lipid, thiab carbohydrate metabolism. Basal metabolic indexes tau nce, thiab decomposition ntawm fatty acids thiab qabzib hauv aerobic ATP synthesis tau nrawm.

SR 9011 cov txiaj ntsig ntawm Regulates circadian rhythms

Cov txheej txheem physiological ntawm cov metabolism thiab kev coj tus cwj pwm, xws li kev ua si / so, feem ntau yog tsim nyob rau hauv kwv yees li 24 teev cycles uas tau tsav los ntawm circadian rhythms. Lub nuclear receptors rev-viral erythroblastosis thiab (ReV-ERB thiab ) tswj cov kev qhia ntawm cov core moos proteins thiab yog li pab txhawb rau circadian atherosclerosis. Thaum lub cev raug cuam tshuam los ntawm circadian atherosclerosis thiab qeeb metabolism, SR 9011 tuaj yeem thim rov qab cov txiaj ntsig ntawm circadian atherosclerosis ntawm lub cev mus rau qee yam thiab ua kom cov metabolism hauv.

SR 9011 modulates cov teebmeem ntawm circadian rhythms uas ua rau lub cev tsim kom muaj kev so zoo dua, zoo dua hmo ntuj, thiab ua kom tsaug zog.

Nyob rau hauv feem ntau cov kev tshawb fawb, SR 9011 tau pom tias ua kom tag nrho cov qauv qhia ntawm circadian rhythms thaum nas tau khaws cia hauv qhov tsaus ntuj, tso cai rau lawv ua haujlwm zoo li thaum nruab hnub.

SR 9011 rau bodybuilding Ua bodybuilder ceeb toom thiab tsom. Yog li ntawd, koj yuav pw tsaug zog zoo dua thaum so thiab mam li npaj tau zoo dua rau kev dhia dej rau hauv lub cev thiab ua haujlwm rau hnub tom qab.

SR 9011 cov txiaj ntsig ntawm Kev Txhim Kho kev muaj peev xwm kis las

Kev ua kom lub zog ntawm cov receptor nuclear REV - ERB nce kev tawm dag zog los ntawm kev nce cov mitochondria hauv cov leeg pob txha. Mitochondria yog lub zog ntawm cov hlwb. Kev nce ntawm mitochondria hauv cov leeg tuaj yeem txhim kho kev ua siab ntev thiab cov leeg nqaij ntawm cov neeg siv, yog li txhim kho lawv lub peev xwm ua haujlwm.

SR 9011 nce oxygenation peev xwm thiab txhim kho oxygenation mus rau qhov ntsuas tau. SR 9011 rau kev tsim lub cev pab txhim kho kev ua siab ntev thiab yog li kev ua kis las.

SR 9011 txo cov piam thaj hauv lub cev tsis muaj kev cuam tshuam rau insulin; Kev nqus dej ntau ntxiv rau hauv cov leeg, ua rau cov lus teb sai dua thiab ua haujlwm zoo dua.

SR 9011 cov txiaj ntsig ntawm Kev Txhim Kho lipid metabolism

Lub nuclear receptor REV - ERB yog lub hauv paus rau lipid thiab qabzib metabolism, thiab los ntawm kev ua ncaj qha rau lawv, qhov tseem ceeb ntawm lub zog tuaj yeem tau txais.

SR 9011 ua rau kom cov metabolism hauv so, nrog rau kev hloov pauv hauv cov metabolism hauv kev ua kom lub zog tso zis los ntawm 5% txawm tias thaum lub cev ua haujlwm so. Raws li qhov tshwm sim, SR 9011 hlawv cov calories ntau dhau thiab tiv thaiv lawv los ntawm kev hloov mus rau hauv cov rog hauv lub cev, uas, nrog rau kev txhim kho cov piam thaj metabolism, ua kom muaj roj zoo.

Hauv kev sim nrog cov nas, nws tau pom tias cov nas SR 9011 poob txog 10% ntawm lawv lub cev hnyav thaum muab cov zaub mov qub txhua hnub.

Thaum SR 9011 yog siv los ua ib qho receptor nyob rau hauv daim siab, lub synthesis ntawm lipids, cholesterol thiab fatty acids yog qeeb. Thaum SR 9011 nkag mus rau hauv cov ntshav, qib ntawm triglycerides, tag nrho cov roj cholesterol thiab LDL raug txo. Kev siv mus ntev tuaj yeem txo cov kab mob rog rog thiab muaj txiaj ntsig zoo rau cov hlab plawv.

SR 9011 cov txiaj ntsig ntawm Pab tsim cov leeg nqaij ntshiv

Lub nuclear receptor REV - ERB noob qhia tau nce nyob rau hauv cov leeg pob txha, thiab fatty acid thauj mus rau hauv cov leeg nqaij pob txha tau txhim kho. Muab cov txiaj ntsig saum toj no ua ke, Dab tsi Cov Neeg Siv muaj yog lub peev xwm los tawm dag zog thiab ntev dua, uas tuaj yeem txhawb cov leeg nqaij rov qab zoo dua tom qab kev tawm dag zog, thiab pab tus neeg tsim lub cev rov ua kom cov leeg zoo dua.

Qhov tseeb, SR 9011 rau Bodybuilding tsis ua ncaj qha rau cov leeg nqaij, tab sis bodybuilder tau xaiv nws lawm vim tias cov teebmeem SR 9011 ua tiav, ncaj qha lossis tsis ncaj, pab lub cev tsim cov leeg.

Nws tau pom tias tom qab siv SR 9011, cov leeg nqaij muaj peev xwm rov tsim dua sai dua thaum lub sijhawm so, uas tau ua tiav los ntawm kev txhawb nqa qhov sib txawv ntawm myoblasts. Qhov tshwm sim yog tias cov kua muag me me tau kho sai dua tom qab kev tawm dag zog, ua rau cov leeg nqaij loj hlob.

Qhov kev kho muaj peev xwm ua rau lub cev tsim kom muaj zog ntau dua ntawm cov leeg nqaij los ntawm kev tawm dag zog thiab ntev dua. SR 9011 rau kev tsim lub cev, cov leeg nqaij yuav kho thiab loj hlob sai, thiab cov rog yuav txo qis hauv cov txheej txheem.

SR 9011 yog ib qho kev ua kom nrawm nrawm (txhim kho kev ntxhov siab hauv 25 feeb ntawm kev noj).

Txawm hais tias SR 9011 tseem tab tom kawm thiab tsis tau sim hauv tib neeg tab sis ntau tus neeg tsim lub cev xav tau 10 mg rau 30 mg ib hnub ntawm SR9011 ntau npaum li cas hauv lawv lub voj voog.

SARM SR9011 Bodybuilding, 10 mg / hnub feem ntau yog thawj koob tshuaj, tom qab ntawd qhov koob tshuaj ntau tshaj tsis pub tshaj 30 mg / hnub. Yog tias koj yog thawj zaug siv cov khoom siv no, sim los ntawm 10mg thiab ntxiv rau hauv 2-3 lub lis piam rau koj tus kheej zoo tshaj plaws SR9011 Dosage.

Raws li peb txhua tus paub, SR 9011 tsis yog anabolic, tsis tau pom muaj kev cuam tshuam tsis zoo hauv kev tshawb fawb tsiaj, yog li nws raug txiav txim siab siv mus ntev. Txawm li cas los xij, SR 9011 tseem nyob rau theem kev sim thiab tsis tau sim rau tib neeg, yog li cov kev mob tshwm sim tiag tiag tsis paub txog kev sim.

Bodybuilder feem ntau pom tias SR 9011 rau lub cev tsim tau zoo zam thiab tsis muaj teeb meem siv mus ntev. Qhov tsuas caveat yog tias nws cuam tshuam rau tus neeg siv lub circadian atherosclerosis. Qhov no txhais tau hais tias siv SR 9011 rau kev tsim lub cev yuav ua rau muaj teeb meem pw tsaug zog.

Yog tias koj siv cov koob tshuaj ntev ntev, koj yuav hnov ​​​​zoo dua thiab cob qhia lawv lub cev kom tsis txhob tsaug zog. Yog li tsis txhob siv SR 9011 hauv cov koob tshuaj siab thiab ntev ntev.

Qhov koob tshuaj ntau tshaj yuav tsum tsis pub tshaj 30 mg / hnub, thiab lub voj voog ntev tshaj plaws yuav tsum tsis pub tshaj 12 lub lis piam.

Siv SARM SR9011 rau Bodybuilding ib leeg pab lub cev tsim kom muaj zog, rov ua kom cov leeg, thiab tsaug zog.

Txawm li cas los xij, SR 9011, thaum siv ua ke nrog anabolic SARM, ua kom muaj zog muaj zog, ua kom lub sijhawm rov qab los, ua kom cov leeg kho thiab loj hlob, thaum hlawv ntau rog thiab nyob twj ywm.

Vim tias cov yam ntxwv no, SR 9011 rau kev tsim lub cev tuaj yeem siv rau kev sib tw, nthuav dav, txiav, lossis kev saib xyuas, thiab txawm tias tom qab kev caij tsheb kauj vab lossis caij tsheb kauj vab txuas ntxiv.

Vim li cas SR 9011 muaj rau kev caij tsheb kauj vab tom qab? Qhov no yog vim SR 9011 tiv thaiv qhov poob ntawm lub zog los ntawm kev poob qib testosterone hauv lub cev. Txoj kev no, thaum PCT, thaum qib testosterone tseem rov zoo, koj tseem tuaj yeem tau txais lub zog txhawb zog, tso cai rau koj ua kom qoj ib ce thiab hlawv rog, thiab zam kev poob ntawm cov leeg nqaij uas tshwm sim thaum PCT.

●SR 9011 rau bodybuilding stacking rau expansion lub hom phiaj yog raws li nram no (ntau tshaj lub sij hawm ntawm 12 lub lis piam):
●SR 9011 10 mg / hnub
●RAD 140 10 mg / hnub
●MK 677 10 mg / hnub
●LGD 4033 5 mg / hnub
●SR 9011 rau bodybuilding yog pawg rau txiav lub hom phiaj raws li hauv qab no:
●SR 9011 20 mg / hnub
●RAD 140 15 mg / hnub
●MK 2866 25 mg / hnub

Muaj ob hom nuclear receptor Rev-ERB agonists: Rev-ERB thiab Rev-ERB .

SR 9011 thiab SR 9009 yog ReV-ERB receptor agonists.

GW 501516 yog PPARδ receptor modulator.

Tsuas yog pom los ntawm qhov xwm txheej ntawm lawv, SR 9011 thiab SR 9009 ua haujlwm tib yam thiab sib txawv nrog GW 501516. Yog li, thaum twg rau kev tsim lub cev, qhov txawv ntawm SR 9011 rau bodybuilding yog dab tsi thaum piv nrog SR 9009 thiab GW 501516.

SR 9011 thiab SR 9009 yog ob qho tib si ReV-ERB receptor agonists.

SR 9011 cuam tshuam rau circadian tshuav nyiaj li cas ntau dua, thaum SR 9009 tsom ntau dua ntawm fatty acid thiab qabzib metabolism.

Qee tus kws tsim lub cev tsis hnov ​​​​qhov txawv ntawm SR 9009 rau kev tsim lub cev thiab SR 9011 rau kev tsim lub cev txhua lub sijhawm, thaum qee tus kws tsim lub cev qhia tias lawv xav tias qhov txawv.

Cov teebmeem ntawm SR 9009 rau bodybuilding thiab SR 9011 rau bodybuilding yog qhov tseem ceeb tib yam, tshwj tsis yog tias lawv cuam tshuam los ntawm circadian rhythms.

Kev sib piv ntawm lawv cov qauv molecular qhia tau hais tias SR 9011 yog peb ntau hydrocarbon chains ntev dua SR 9009, thiab -NH- ( pawg amine) tau hloov -O- (carbonyl pawg).

Qhov no ua rau SR 9011 ntau bioavailable thiab muaj ib nrab neej ntev dua SR 9009.

Raws li kev sib xyaw ua ke ntau dua li SR 9011, SR 9009 tau lees paub dav dav hauv kev ua kom muaj zog. SR 9009 muaj txiaj ntsig zoo, tab sis nws cov bioavailability tsis yog qhov tshwj xeeb siab.

Cov -NH- ( pawg amine) hauv SR 9011 txhim kho nws cov bioavailability thiab ua rau nws ua tau zoo dua.

Qhov ntev ntawm cov saw hlau hydrocarbon ncaj qha cuam tshuam rau ib nrab-lub neej ntawm cov khoom sib xyaw. Qhov luv luv ib nrab-lub neej ntawm SR 9009, uas yog kwv yees li 4 teev, ua rau SR 9009 yuav tsum tau siv ntau zaus, nrog rau cov koob tshuaj ntau dua 2-4 zaug hauv ib hnub.

SR 9011 muaj ib txoj hlua hydrocarbon ntev dua, ua rau nws zoo li kev siv ib zaug ntawm SR 9011 yuav kav ntev dua li ntawm SR 9009, txog ob zaug ntev. Lub neej ib nrab ntev tso cai rau peb txhaj tshuaj tsawg dua.

Qhov no ua rau SARM SR9011 rau bodybuilding ib tug zoo lwm txoj.

Cov npe lag luam	TIAB SA 9011
CAS	1379686-29-9
Molar loj	479.04
MF	C23H31ClN4O3S
Purity	Tshaj 98%
Yam khoom	Dawb Cyrstalline hmoov

 

 

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SR 9011 yog ib tug nuclear receptor ReV-ERB agonist.

cardarine ua raws li PPARδ receptor modulator.

Cov txiaj ntsig tseem ceeb ntawm cardarine rau kev tsim lub cev yog ua kom lub zog thiab kev ua siab ntev, thaum cov txiaj ntsig tseem ceeb ntawm SR 9011 rau kev tsim lub cev yog tswj hwm circadian atherosclerosis, cuam tshuam cov metabolism, thiab txo cov txheej txheem ntawm adipogenesis.

GW 501516 muaj ib nrab-lub neej ntev ntawm 24 teev dua li SR 9011 thiab tuaj yeem siv ib hnub ib zaug.

GW 501516 yog cov khoom lag luam uas paub tab uas tam sim no nyob rau theem II kev sim tshuaj. Tseem tsis tau muaj kev sim tib neeg rau SR 9011.

GW 501516 yog qhov zoo dua los txo qhov mob.

SR 9011 rau kev tsim lub cev muab kev pw tsaug zog zoo dua li GW 501516. Lub SR 9011 kuj txo kev ntxhov siab thiab ntxhov siab.

Los ntawm kev sib piv SR 9011 vs SR 9009 vs GW 501516, Yog tias koj xav txhim kho kev ua siab ntev, koj tuaj yeem xaiv GW 501516 hauv qhov tshwj xeeb. Yog tias koj xav tau cov txiaj ntsig ntau dua, koj tuaj yeem xaiv SR 9011 lossis SR 9009. Sib piv SR 9011 nrog SR 9009, SR 9009 rau kev tsim lub cev yog qhov paub tab, tab sis SR 9011 rau kev tsim lub cev muaj qhov zoo ntawm lub neej ntev dua thiab ntau dua bioavailability.

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