Dapoxetine Raw Cov Khoom Siv Hmoov Hmoov Siv Kom Ua Ntej Ejaculation Ua Ntej: 129938-20-1

Dapoxetine raw khoom hmoov?

Dapoxetine hydrochloride raw khoom hmoov yog cov ntshiab, crystalline chaw uas ua haujlwm ua cov tshuaj nquag PE PE XA. Chemically, nws tau cais ua xaiv cov serotonin ruptives (SSRI). Txawm li cas los xij, nws txoj kev loj hlob yog qhov tseem ceeb tawm los ntawm Tsoos SSris siv rau kev mob nyuab siab thiab ntxhov siab. Tsis zoo li nws cov counterparts (piv txwv li, fluoxetine, paroxetine), uas tau tsim los rau mob ntev, ntev}}}}} {}}}} Thov siv rau tus PE. Nws molecular qauv tau optimized rau kev ua kom sai thiab tshem tawm, ib qho kev sib txawv uas sib txawv nws ntawm lwm tus SSRIS.

Qhov "raw khoom" lossis "API hmoov" yog feem ntau yog ib tug dawb kom tawm - dawb, zoo crystalline hmoov. Nws yog muaj zog thiab tau ua raws li kev tswj hwm ib puag ncig hauv kev tsim kev tsim khoom (GMP) kom ntseeg tau tias muaj kev sib cav sib ceg (cov khoom xyaw tsis ua haujlwm) los tsim cov ntsiav tshuaj.

Cov yam ntxwv ntawm cov hmoov nplej yog lub hauv paus rau nws txoj haujlwm thiab tuav:

1.High huv huv qib qib:Kws Tshuaj Kho Mob - qib qib dapoxetine hmoov yuav tsum tau ua kom tiav raws li 99.5%) raws li txhais los ntawm cov kws muag tshuaj tseem ceeb li USP lossis EP. Qhov no ua kom pom tseeb thiab kev nyab xeeb hauv cov khoom kawg, pub dawb los ntawm cov teeb meem impurities.

2.hygroscopicity:Cov ntsev ntawm hydrochloride tuaj yeem hygroscopic, lub ntsiab lus nws zoo li nqus dej noo los ntawm huab cua. Cov cuab yeej no yog qhov tseem ceeb rau cov tuam ntxhab, raws li txheej txheem uas cov hmoov yuav tsum tau muab ntim rau hauv cov av noo kom tiv thaiv kev ua kom tsis txhob muaj kev txwv thiab clumping.

3.rapid pharmacokinetic profile (inerent cov cuab yeej):Qhov tseem ceeb tshaj plaws yog intrinsic rau lub molecule nws tus kheej: nws tau nrawm nrawm ntawm kev ua thiab luv ib nrab- lub neej. Qhov no tsis yog los ntawm kev tsim tawm tab sis ntawm Molecule tus qauv tsim. Nws yog nrawm heev thiab metabolized, uas yog tag nrho cov hauv paus rau nws ntawm - Thov siv.

4.Potency:Raws li ib tug hmoov nplej siav, nws yog muaj zog heev. Dosing yog ntsuas hauv milligrams, nws yuav tsum ua kom pom cov khoom siv thiab ceev faj kev sib kis lossis tsis siv tshuaj tiv thaiv thaum lub sijhawm tsim khoom.

Tus thiab thawj daim ntawv thov ntawm Dapoxetine HCL Raw Khoom yog tusKev tsim cov tshuaj ntawm cov kws tshuaj rau kev kho mob ntawm kev ua ntej ejaculation.

● - teev cov tshuaj lag luam tshuaj:Nov yog nws daim ntawv thov feem ntau. Cov tuam txhab kev lag luam loj yuav cov API hauv ntau cov ntaub ntawv ua tiav noj (FDC), xws li zaj duab xis- Cov ntsiav tshuaj (piv txwv li 30 mg thiab muaj zog). Cov txheej txheem cuam tshuam nrog cov khoom siv API, sib xyaw ua ke ntawm cov apri, sib xyaw, thiab cov roj av, thiab tom qab ntawd ua kom sib xyaw sib xyaw rau hauv cov ntsiav tshuaj.

Revource Kev Siv Lub Chaw Muag Tshuaj:Hauv qee thaj tsam, cov chaw muag tshuaj tshwj xeeb tau txais cov hmoov API los tsim cov qauv rau cov neeg mob. Qhov no tuaj yeem suav nrog kev tsim kho cov tshuaj kho mob (piv txwv li, 45 mg) rau cov neeg uas poob ntawm cov ntsiav tshuaj lossis kev ncua ntawm qhov nyuaj nqos tshuaj. Daim ntawv thov no yog cov tswj hwm zoo heev thiab yuav tsum tau tshuaj los ntawm kws kho mob muaj ntawv tso cai.

Nws yog qhov tseem ceeb rau lub xeev uas cov hmoov nplej nyoos nws tus kheejtsis yog npaj rau kev coj ncaj qha rau tib neegCov. Yog tias tsis muaj cov tshuaj tswj zoo nkauj thiab cov qauv tsim los ntawm cov khoom siv roj carbon monoxide, tus kheej {}}}}}}}}}}}} Ention} Kev coj mus rau ntau ntau yam, kev tsis zoo, lossis kev lom zem.

Dapoxetine lub efficacy stems los ntawm nws cov tshuab ntawm kev ua nyob rau hauv nruab nrab lub paj hlwb.

● Mechanism:Nws ua haujlwm li cov SSRI. Serotonin yog ib tug neurotransmitter paub los ua lub luag haujlwm tseem ceeb hauv kev tsim kho ejaculatory reflex. Los ntawm inhibiting nws rov qab mus rau hauv lub presynaptic neuron, dapoxetine nce ntxiv cov serotonin ntau theem hauv synaptic cleft. Qhov no ua kom zoo rau serotonergic nurotransmission yog ntseeg kom nce neuro {{}}} }ibitory} control tswj dua lub ejaculatory reflex, yog li ncua ejaculation.

● Cov txiaj ntsig (kho cov txiaj ntsig):

Notsistly nce intravaginal ejaculatory lub sijhawm latency (ielt):Cov kev sojntsuam cov kev tshawb fawb tas li qhia txog 2.5 txog 3-khawm nce hauv ielt piv rau placebo.

○ Txhim khu kev tswj hwm ntawm kev ejaculation:Cov txiv neej qhia txog kev paub ntau dua ntawm kev tswj hwm lub sijhawm ntawm lawv lub ejaculation.

○ Enhanced deev txaus siab:Qhov nce latency thiab txhim kho kev tswj hwm ua rau muaj kev txaus siab ntau dua rau tus neeg mob thiab nws tus khub.

○ Thaum -} Thov koob tshuaj:Tsis zoo li cov neeg mob nyob rau hauv lub limtiam uas muaj kev sib daj sib deev

Cov kev ntsuas no tau txhais rau cov khoom tiav kws tshuaj, uas muaj cov tshuaj API pre-a pried.

● Dosage:Qhov kev pom zoo pib koob tshuaj yog 30 mg, coj los ntawm dej li ntawm 1 mus rau 3 teev ua ntej xav kev sib deev. Cov koob tshuaj yuav tau nce ntxiv rau 60 mg raws li kev ua tau zoo thiab thev taus. Nws yuav tsum tsis txhob noj ntau tshaj ib zaug txhua 24 teev. Qhov koob tshuaj no tsuas yog ua tau vim yog cov tshuaj SHAPE lub chaw muag tshuaj.

● "kev voj voog" (ib tug misnomer):Tsis zoo li cov ua haujlwm -} kev txhim kho cov tshuaj siv hauv kev ua kom lub cev uas tau khiav hauv "voj voog," Dapoxetine tsis siv cyclically. Nws yog ib lub -}} siv, ntawm - Thov siv tshuaj. Tsis muaj txhais "ntawm" lossis "tawm". Nws raug coj raws li xav tau rau kev sib deev. Ntev {- sijhawm, siv kev siv sib txawv tau raug kawm thiab yog txiav txim siab nyab xeeb rau kev saib xyuas kev kho mob.

Ib nrab - lub neej:Ib nrab - lub neej yog lub hauv paus ntawm Dapoxetine txoj haujlwm ua haujlwm. Nws txhais tau tias kev tshem tawm ib nrab - lub neej yog kwv yees li90 feeb (1.5 teev)Cov. Qhov no yog zoo tshaj plaws luv piv rau lwm tus SSRIS, uas muaj ib nrab- lub neej li ntawm 24 teev mus rau ntau hnub. Lub luv luv ib nrab - lub neej tso cai rau:

○ Ua Haujlwm Pib:Nws ncav cuag lub siab ntshav ntshav (tmax) hauv li 1-2 teev, sib dhos nrog nws cov koob tshuaj tiv thaiv.

○ Tshem tawm sai sai:Cov tshuaj tau tshem tawm sai sai ntawm lub cev tom qab nws npaj ua tau zoo, txo qis kev ua yeeb yam rau kev phiv tshuaj thiab txo qhov tshwm sim ntawm cov tshuaj. Nws yog metabolized tetensively nyob rau hauv daim siab los ntawm ntau enzymes (cyp3A4, Cyp2D6, CYP2C19, thiab lwm yam) thiab tawm hauv cov zis.

Kev Lag Luam Npe	Kutub, priligy, Duratia, Pentenal-30, Sustinex, Lejam, Dumax
Cas	119356-77-3,129938-20-1
Tus hniav loj	305.421
Mf	C21H23Tsis muaj
Kev coj dawb huv	Saum toj no 98%
Kev tsim nyog	Dawb crystalline hmoov

 

 

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Dapoxetine hydrochloride raw khoom hmoov tau deb tshaj li ib qho tshuaj lom neeg; Nws yog embodiment ntawm hom phiaj tsim qauv. Nws cov hav zoov yog cov lus teb ncaj qha rau cov kev xav tau tshwj xeeb rau ib qho ntawm - Thov kev kho mob thiab muaj kev ntxhov siab. Nws cov kev txhais nta - kev coj zoo, thiab tseem ceeb tshaj plaws, ib qho tseem ceeb ntawm cov chaw muag tshuaj, ib qho tseem ceeb, ua rau nws ua daim ntawv thov. Thaum lub sij hawm cov txiaj ntsig ntawm kev txhim kho kev tswj hwm thiab kev txaus siab yog pom tau los ntawm qhov kawg {6} Tus neeg siv khoom, lawv txhua tus muaj kev tshawb fawb txog kev tsim khoom thiab cov qauv no siv API. Nws sawv ntsug raws li qhov tseeb uas cov tshuaj niaj hnub tuaj yeem ua cov tshuaj qub uas muaj peev xwm tsim cov khoom siv qub los ntawm kev txiav txim siab ntawm tib neeg kev xav tau. Nws siv seem, thiab yuav tsum nruj me ntsis nyob twj ywm, hauv lub realm ntawm kev tshawb fawb screen thiab kev kho mob.

Cim npe nrov: Dapoxetine Raw Khoom Kho Hmoov Rau Kev Kho Mob Ejaculation Ua Ntej: 129938-20-1 Cov Khoom Siv, Cov Chaw Tsim Khoom, Chaw Tsim Tshuaj