Benzocaine CAS: 94-09-7

Benzocaine cov tshuaj muaj cov khoom xyaw nquag Benzocaine, belongs rau pab pawg ntawm cov tshuaj loog hauv zos qhia hauv cov xwm txheej hauv qab no:
Kev kho mob thiab tsis xis nyob hauv cov kab mob: Mob caj pas, mob me me ntawm daim tawv nqaij, cov rau tes ingrown, khaus qhov chaw mos los yog qhov quav, muv stings, hemorrhoids, kab tom, mob hniav, qhov ncauj thiab cov pos hniav khaus, mob otitis externa, otitis media; Inhibits ejaculation ntxov ntxov thaum pw ua ke; Siv tshuaj loog ntawm lub qhov ncauj, caj pas, qhov ntswg, qhov chaw mos, qhov quav, lossis loog ntawm daim tawv nqaij kom txo tau qhov mob thaum xav tau cov cuab yeej kho mob.
Pharmacodynamics: Benzocaine belongs rau pawg tshuaj loog hauv zos nrog cov qauv ester. Lub mechanism ntawm kev txiav txim ntawm cov tshuaj yog reversibly inhibit lub depolarization ntawm lub neuronal membrane nrog rau cov ion pauv, yog li tiv thaiv lub depolarization ntawm cell membrane thiab txo cov kev sib kis ntawm paj hlwb impulses. hnov nyob ze ntawm qhov chaw txhaj tshuaj.
Pharmacokinetics Absorption: Benzocaine yog absorbed sai heev los ntawm cov tawv nqaij puas thiab mucous daim nyias nyias. Kev faib tawm: Benzocaine khi rau ob qho tib si alpha-1-acid glycoprotein thiab serum albumin. Metabolism: Benzocaine yog metabolized los ntawm 3 cov tshuaj tiv thaiv nrog rau acetylation rau acetylbenzocaine, ester hydrolysis rau 4-aminobenzoic acid thiab N - hydroxylation rau benzocaine hydroxide. 4-aminobenzoic acid yog tom qab ntawd acetylated los ua 4-acetaminobenzoic acid, uas kuj yog cov khoom ntawm hydrolysis ntawm acetybenzocaine ester.
Kev tshem tawm: Cov tshuaj raug tshem tawm raws li metabolites hauv cov zis.

 

 

Cov koob tshuaj Benzocaine koob tshuaj yog nyob ntawm lub hnub nyoog thiab tus mob ntawm tus neeg mob, tshwj xeeb hauv qab no:
Cov neeg laus:
Kev kub nyhiab me me, muv stings, kab tom, tshav kub: Siv cov tshuaj Benzocaine txaus. 5 - 20% ntawm thaj chaw cuam tshuam txhua 6-8 teev; Mob caj pas: Nias ntawm ib ntsiav tshuaj Benzocaine, rov ua dua koob tshuaj txhua 2 teev, thiab noj mus txog 2 hnub. Los yog siv tshuaj tsuag qhov ncauj 4 zaug hauv ib hnub (rau daim ntawv no, nplawm cov tshuaj tawm tom qab 1 feeb ntawm txau); Hemorrhoids: Siv cov tshuaj pleev ib ce 5 - 20%, siv rau qhov txhab thiab rov ua dua txhua 4 teev; Kev Kho Hniav: Siv Benzocaine 2.5 - 20% tshuaj raws li xav tau; Cov pob khaus: Siv ib qho nyiaj txaus ntawm Benzocaine 20% rau thaj tsam cuam tshuam, rov ua dua txhua 12 teev; ejaculation ntxov ntxov: Siv Benzocaine 7.5% siv me me rau qhov noov li ntawm 15-20 feeb ua ntej kev sib deev thiab yuav tsum tau ntxuav tawm tom qab kev sib deev; Mob otitis externa, otitis media: Muab li ntawm 4-5 tee ntawm Benzocaine 20% tov, ces siv paj rwb swabs ntxig rau hauv pob ntseg los tiv thaiv cov tshuaj ntws tawm. Rov muab tshuaj dua tom qab 1-2 teev yog tias tsim nyog.
Cov menyuam yaus:
Benzocaine rau mob hniav vim qhov tshwm sim tshiab: Tsis txhob siv rau cov menyuam yaus hnub nyoog qis dua 4 xyoos. Cov menyuam yaus hnub nyoog 4 xyoos thiab laus dua siv cov tshuaj Benzocaine 7 kom txaus. Cov pob khaus, muv stings, kub hnyiab me me, kab tom, tshav kub hnyiab, cov pos hniav thiab qhov ncauj khaus: Rau cov menyuam yaus hnub nyoog tshaj 2 xyoos nkaus xwb, qhov ntau npaum yog tib yam rau cov neeg laus; Kev khaus ntawm cov pos hniav thiab qhov ncauj: Rau cov menyuam yaus hnub nyoog qis dua 2 xyoos, qhov koob tshuaj yog tib yam rau cov neeg laus; Mob caj pas: Tsuas yog siv rau cov menyuam yaus hnub nyoog qis dua 5 xyoos, qhov koob tshuaj yog tib yam li cov neeg laus; Hemorrhoids: Siv tsuas yog rau cov menyuam yaus hnub nyoog qis dua 12 xyoos, qhov koob tshuaj yog tib yam li cov neeg laus.
Kev noj tshuaj ntau dhau thiab kev kho mob Overdose: Kev noj ntau dhau ntawm Benzocaine tuaj yeem tshwm sim cov tsos mob lom xws li hauv nruab nrab lub paj hlwb kev nyuaj siab, plawv tsis ua haujlwm, bradycardia, plawv nres. , arrhythmias, hypotension, convulsions thiab syncope. Tsis tas li ntawd, kev siv tshuaj ntau dhau tuaj yeem ua rau methemoglobinemia ua rau cyanosis, ua pa tsis ua haujlwm.
Kev kho mob nyob rau hauv cov ntaub ntawv ntawm overdose: Cov tsos mob ntawm overdose thiab kev txhawb nqa kev kho mob xws li kev tswj ntawm qaug dab peg, kev saib xyuas ntawm cov pa. Cov neeg mob uas muaj hypermethaemoglobinemia yuav tsum tau kho nrog methylene blue intravenous.

Contraindications Contraindicated siv Benzocaine nyob rau hauv cov ntaub ntawv hauv qab no:
Cov neeg uas nkag siab zoo rau Benzocaine lossis tshuaj loog hauv zos ntawm pawg caine xws li butacaine, procaine; Cov neeg mob uas muaj ntshav qab zib, laryngitis (contraindicated siv tshuaj tsuag qhov ncauj); Cov neeg mob uas xav tias lossis keeb kwm ntawm methaemoglobinemia; Cov neeg mob uas noj cholinesterase inhibitors ib txhij lossis raug kho nrog tshuaj ntawm sulfonamide pawg; Benzocaine yog contraindicated rau kev siv ntawm hlwv, thaj chaw loj ntawm daim tawv nqaij, qhib qhov txhab, kis kab mob los yog sunburn. Siv ceev faj thaum siv cov tshuaj hauv cov ntsiab lus hauv qab no:
Cov neeg mob bronchitis, bronchial hawb pob, emphysema; Cov neeg mob plawv; Tus neeg mob haus luam yeeb; Cov menyuam yaus; Cov poj niam cev xeeb tub thiab lactating; Saib xyuas cov tsos mob thiab cov tsos mob ntawm anemia hauv cov neeg mob tau kho nrog benzocaine.
Cov lus ceeb toom thaum siv Benzocaine Cov ntawv sau thaum siv Benzocaine yog raws li hauv qab no:
Tsis txhob kho nrog Benzocaine ntev (pom zoo tsis pub tshaj 7 hnub); Kev siv tshuaj uas yuav npog cov tsos mob ntsig txog tus mob; Tsis txhob ntau tshaj qhov pom zoo ntawm cov tshuaj; Tsis txhob siv cov tshuaj hauv cov neeg mob uas muaj lub plawv nres; Nyob rau hauv cov ntaub ntawv ntawm kev siv tshuaj ntawm gingival los yog qhov ncauj mucosa, tsis txhob noj zaub mov rau 1 teev tom qab noj cov tshuaj; Rau cov poj niam cev xeeb tub, Benzocaine belongs rau pawg C. Yog li ntawd, nws yuav tsum tsuas yog siv rau hauv cov pej xeem no thaum cov txiaj ntsig zoo tshaj qhov txaus ntshai; Rau cov poj niam lactating: Tsis muaj kev tshawb fawb txog kev tshem tawm cov tshuaj hauv cov kua mis. Yog li, benzocaine yuav tsum tsis txhob siv rau hauv cov poj niam laus; Rau cov neeg tsav tsheb, cov tshuab ua haujlwm: Cov tshuaj tsis muaj txiaj ntsig.

Qee qhov ua tau tshuaj sib cuam tshuam nrog Benzocaine yog raws li hauv qab no:
Sulfonamide: Cov metabolite ntawm Benzocaine yog para-aminobenzoic acid uas tuaj yeem tiv thaiv cov teebmeem ntawm Sulfonamide. Cholinesterase inhibitors inhibits metabolism ntawm Benzacone. Hyaluronidase tsub kom qhov nqus ntawm benzacoine, ua rau kom cov ntshav cov tshuaj ntau ntxiv thiab exacerbation ntawm cov teebmeem tsis zoo. Technetium Tc - 99m tilmanocept: Benzocaine tuaj yeem txo qhov ua tau zoo ntawm cov tshuaj thaum noj ua ke. Butalbital, Dapsone, Phenytoine, Valproic Acid, Sulfadiazine, Nitroprusside, Nitric Oxide, Quinine noj nrog Benzocaine tuaj yeem ua rau muaj kev pheej hmoo lossis mob hnyav ntawm methemoglobinemia. Cov ntaub ntawv hais txog Benzocaine yuav pab koj nkag siab tias yuav siv nws li cas kom tau txais txiaj ntsig zoo tshaj plaws.

Cov npe lag luam	Lyrica, 3-isobutyl GABA, (S) -3-isobutyl- -aminobutyric acid
CAS	94-09-7
Molar loj	165.189
Formula	C9H11TSIS MUAJ2
Purity	Tshaj 98%
Yam khoom	Dawb crystalline hmoov

 

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Yog lawm, benzocaine yog ib qho tshuaj loog hauv zos uas feem ntau siv los ua qhov mob. Nws belongs rau cov chav kawm ntawm cov tshuaj hu ua ester hauv zos tshuaj loog. Benzocaine ua haujlwm los ntawm kev loog ib ntus lossis thaiv qhov kev hnov ​​​​mob ntawm qhov chaw uas nws tau thov. Nws yog feem ntau siv tshuaj pleev xim rau ntawm daim tawv nqaij los yog mucous daim nyias nyias, xws li sab hauv ntawm lub qhov ncauj los yog caj pas.

Feem ntau siv benzocaine muaj xws li:

Topical Pain Relief:Benzocaine muaj nyob rau hauv ntau yam khoom muag hauv khw, xws li cream, gels, thiab tshuaj pleev, tsim los daws qhov mob ntawm daim tawv nqaij me me, kab tom, sunburn, thiab lwm yam mob.

Kev Siv Kho Hniav:Benzocaine feem ntau siv rau hauv cov khoom siv kho hniav, suav nrog cov gels thiab cov tshuaj nplaum siv rau ntawm cov pos hniav lossis cov hniav kom loog thaj tsam ua ntej qee cov txheej txheem kho hniav. Nws kuj tseem muaj nyob hauv qee cov tshuaj kho qhov ncauj hauv khw muag khoom.

Lub caj pas Lozenges:Qee lub caj pas lozenges los yog tshuaj tsuag rau mob caj pas muaj benzocaine los muab cov caj pas ib ntus, txo qhov tsis xis nyob.

Thaum benzocaine tuaj yeem ua tau zoo rau kev kho mob ib ntus, nws yog ib qho tseem ceeb uas yuav tau siv nws raws li cov lus qhia tau pom zoo thiab kom paub txog cov kev mob tshwm sim lossis kev tsis haum tshuaj. Kev siv ntau dhau lossis siv tsis raug ntawm cov khoom benzocaine tuaj yeem ua rau muaj kev phom sij. Yog tias koj muaj kev txhawj xeeb txog kev tswj qhov mob lossis kev siv benzocaine.

 

 

 

Cim npe nrov: benzocaine cas:94-09-7, Tuam Tshoj benzocaine cas:94-09-7 manufacturers, lwm tus neeg, Hoobkas