Anastrozole, ua lag luam raws li lub npe lag luam Arimidex, yog ib qho uas tsis yog-steroidal aromatase inhibitor siv feem ntau hauv kev kho mob qog noj ntshav hauv cov poj niam postmenopausal. Cov tshuaj no ua haujlwm los ntawm kev txo cov tshuaj estrogen hauv lub cev, uas tuaj yeem ua rau qeeb lossis nres qhov kev loj hlob ntawm qee hom qog mis uas vam khom cov tshuaj estrogen.
Tsim nyob rau xyoo 1990, anastrozole tau txais kev pom zoo los ntawm FDA hauv xyoo 1995 thiab txij li ntawd los tau dhau los ua lub hauv paus hauv kev kho tshuaj hormone rau mob qog noj ntshav. Nws cov txheej txheem ntawm kev ua haujlwm suav nrog kev xaiv inhibiting aromatase enzyme, uas yog lub luag haujlwm rau hloov androgens rau hauv estrogen. Los ntawm kev thaiv qhov kev hloov pauv no, anastrozole ua tau zoo txo qis cov tshuaj estrogen, tshwj xeeb tshaj yog nyob rau hauv cov poj niam postmenopausal qhov twg zes qe menyuam tsis yog thawj qhov chaw ntawm estrogen.
Anastrozole feem ntau yog tshuaj raws li 1 mg ntsiav tshuaj noj ib zaug ib hnub, nrog lossis tsis muaj zaub mov. Nws yog siv nyob rau hauv ntau yam mob cancer ntawm lub mis, nrog rau kev kho mob rau cov tshuaj hormones thaum ntxov receptor-zoo mob qog noj ntshav mis, raws li kev kho thawj kab rau kev mob qog noj ntshav lossis mob qog noj ntshav, thiab nyob rau hauv cov xwm txheej uas mob qog noj ntshav tau nce txawm tias tamoxifen kho.
Thaum ua tau zoo, anastrozole tuaj yeem ua rau muaj kev phiv xws li kub kub, mob pob qij txha, tsis muaj zog, hloov mus rau lub siab, thiab muaj kev pheej hmoo ntawm pob txha. Nws yog ib qho tseem ceeb uas yuav tsum nco ntsoov tias cov tshuaj no tsis haum rau cov poj niam premenopausal lossis thaum cev xeeb tub vim nws cov txheej txheem ntawm kev txiav txim thiab muaj feem cuam tshuam rau fetal.
Kev taw qhia ntawm anastrozole thiab lwm yam aromatase inhibitors tau txhim kho thaj chaw kho mob zoo rau cov neeg mob qog noj ntshav tom qab yug menyuam. Cov tshuaj no feem ntau qhia tau hais tias muaj txiaj ntsig zoo dua thiab muaj txiaj ntsig zoo dua qhov tshwm sim piv rau cov kev kho mob laus xws li tamoxifen, tshwj xeeb tshaj yog hais txog kev txo qis kev pheej hmoo ntawm mob qog noj ntshav thiab txhim kho tag nrho cov ciaj sia nyob hauv cov neeg mob tsim nyog.
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