Clomiphene Citrate 50 Mg Stimulation Of Ovulation CAS: 911-45-5
Clomid yog lub npe tshuaj rau clomiphene citrate, cov hmoov uas tsis yog tshuaj steroidal pom zoo hauv xyoo 1967 los ntawm Food and Drug Administration (FDA) siv los ua cov tshuaj fertility. Nws belongs rau ib chav kawm ntawm cov tshuaj hu ua ovulatory stimulants. Rau kev noj, cov hmoov yog nias rau hauv cov ntsiav tshuaj me me, feem ntau dosed ntawm 50 milligrams ib ntsiav tshuaj.
Clomid yog lub npe tshuaj rau clomiphene citrate, cov hmoov uas tsis yog tshuaj steroidal pom zoo hauv xyoo 1967 los ntawm Food and Drug Administration (FDA) siv los ua cov tshuaj fertility. Nws belongs rau ib chav kawm ntawm cov tshuaj hu ua ovulatory stimulants. Rau kev noj, cov hmoov yog nias rau hauv cov ntsiav tshuaj me me, feem ntau dosed ntawm 50 milligrams ib ntsiav tshuaj.
Txawm hais tias muaj ntau yam kev kho mob fertility yuav tsum tau teem sijhawm nrog tus kws kho mob endocrinologist ntawm lub chaw kho mob tshwj xeeb, Clomid tuaj yeem raug sau los ntawm kws kho mob gynecologist.
Clomid (clomiphene citrate) yog ib qho nonsteroidal, ovulatory stimulant siv los kho ovulatory dysfunction thiab polycystic zes qe menyuam syndrome nyob rau hauv cov poj niam uas, tom qab lwm yam vim li cas rau cev xeeb tub tsis ua hauj lwm raug txiav tawm, muaj siab cev xeeb tub thiab ua raws li cov lus qhia ntxiv uas ua rau cev xeeb tub yuav tshwm sim nrog qhov no. Kev siv tshuaj (saib hauv qab no txog kev siv tshuaj thiab kev siv). Tsis tas li ntawd, cov poj niam no thiab lawv cov phev pub dawb feem ntau yuav tsum tau mus rau ntau qhov kev ntsuam xyuas los ntawm lawv tus kws kho mob OB-GYN ua ntej Clomid pib. Clomid muaj nyob rau hauv daim ntawv generic.
Clomid ua haujlwm li cas?
Hauv luv luv, noj Clomid ua rau koj lub cev tso tawm cov tshuaj hormones uas ua rau muaj feem ntau ntawm koj lub zes qe menyuam tso lub qe loj thiab npaj txhij-rau-fertilized. Qee tus neeg mob noj Clomid ua ib feem ntawm kev kho mob fertility, xws li IUI (Intrauterine insemination) lossis IVF (hauv vitro fertilization) lub voj voog, tab sis ntau tus pib tsuas yog siv Clomid thiab sib deev.
Lub tswv yim yog "sim ua kom muaj qhov sib txawv ntawm cov phev thiab qe lub rooj sib tham," hais tias Kenan Omurtag, MD, tus thawj coj ntawm lub tsev kho mob endocrinology thiab infertility department ntawm Washington University School of Medicine hauv St.
Clomid ua haujlwm los ntawm kev khi rau cov receptors hauv koj lub hlwb uas feem ntau yuav khi nrog cov tshuaj estrogen. Yog li ntawd, koj lub hlwb xav tias koj cov tshuaj estrogen tsawg thiab them nyiaj los ntawm kev tsim ntau FSH, lossis follicle-stimulating hormone, uas tuaj yeem txhawb cov tshuaj estrogen. FSH lub luag haujlwm tseem ceeb yog cuam tshuam txog kev xeeb tub-raws li lub npe txhais tau hais tias, cov tshuaj hormones txhawb koj lub zes qe menyuam, txhawb lawv kom loj hlob. Lub zes qe menyuam follicle yog ib lub hnab me me hauv koj lub zes qe menyuam uas tuav lub qe tsis paub tab, hu ua oocyte. Feem ntau cov poj niam yug los nrog ib tug cia ntawm tsheej lab ntawm cov oocytes uas maj depletes thoob plaws hauv lub neej.
Los ntawm kev ua kom cov follicle loj hlob, FSH pab oocytes loj hlob mus rau hauv cov qe loj. Qhov zoo tshaj plaws, thaum nyob rau Clomid, tsawg kawg yog ib qho ntawm cov qe yuav loj hlob txaus kom tso tawm ntawm cov follicle thiab raug cheb mus rau hauv cov hlab ntsha, qhov chaw uas nws tuaj yeem ntsib nrog cov phev kom fertilized rau hauv lub embryo.
Leej twg yuav tsum noj Clomid?
Yog tias koj tau sim cev xeeb tub los ntawm kev sib deev tsawg kawg ib xyoos (lossis rau rau lub hlis yog tias koj laus dua 34), koj tuaj yeem yog tus neeg sib tw rau Clomid. Clomid feem ntau yog tshuaj rau cov neeg mob uas:
● Unexplained infertility. Nws tuaj yeem ntxhov siab thaum hnov tias tsis muaj lus piav qhia meej rau koj qhov tsis muaj peev xwm xeeb tub. Txawm li cas los xij, koj yuav tau txais qhov kev kuaj mob no yog tias koj muaj kev coj khaub ncaws tsis tu ncua thiab tsawg kawg yog ib txoj haujlwm ua haujlwm, thiab koj tus khub cov phev kuaj tsis qhia txog teeb meem nrog suav lossis kev txav mus los. Txog li 30% ntawm cov niam txiv uas nrhiav kev kho mob fertility raug kuaj pom tias tsis muaj kev piav qhia. Txij li thaum tsis muaj teeb meem txheeb xyuas lub hom phiaj, koj tus kws kho mob yuav zoo li yuav muab tshuaj rau qhov ncauj zoo li Clomid vim tias nws tsis cuam tshuam thiab pheej yig dua piv rau lwm cov kev kho mob fertility.
● Kev coj khaub ncaws tsis xwm yeem. Yog tias koj tsis ovulate raws li lub sij hawm ib hlis twg los yog tsis ovulate tag nrho, koj tus kws kho mob yuav muab tshuaj Clomid los pab txhawb ovulation.
● Polycystic ovary syndrome (PCOS). Cov tib neeg uas muaj PCOS feem ntau muaj lub sijhawm tsis tshua muaj lossis tsis muaj lub sijhawm thiab tej zaum yuav raug tshuaj Clomid. Txawm li cas los xij, US cov lus qhia tam sim no pom zoo kom letrozole, lwm yam tshuaj hauv qhov ncauj, raws li kev kho mob thawj zaug rau cov poj niam uas muaj anovulatory (uas yog hais txog qhov tsis muaj ovulation) PCOS uas tab tom sim xeeb tub, vim tias qhov kev vam meej hauv cov kev tshawb fawb tsis ntev los no tau nce me ntsis nrog. Letrozole piv rau clomiphene citrate.
Clomid Vs. Letrozole
Ib qho aromatase inhibitor, uas yog ib hom tshuaj tiv thaiv kev tsim ntawm estradiol, poj niam cov tshuaj hormones, letrozole feem ntau yog siv los kho mob qog noj ntshav hauv cov tib neeg uas twb dhau los lawm. Txawm li cas los xij, cov kws tshaj lij fertility tam sim no tseem siv nws los pab kho kev xeeb tub hauv cov tib neeg nyob nrog PCOS.
Raws li tau hais los saum toj no, kev tshawb fawb tam sim no qhia tau hais tias letrozole tuaj yeem ua tau zoo dua li Clomid hauv kev pab cov tib neeg nrog PCOS uas tab tom sim xeeb tub (piv txwv li, muaj feem ntau dua ntawm cev xeeb tub thiab yug me nyuam). Tsis tas li ntawd, qhov kev pheej hmoo ntawm qhov tshwm sim tsis zoo, xws li nchuav menyuam, tsis yog siab dua rau cov tib neeg uas noj clomid piv rau cov neeg uas noj letrozole.
Tam sim no, letrozole yog suav tias yog thawj kab ntawm kev kho tshuaj rau cov tib neeg nyob nrog PCOS uas muaj teeb meem xeeb tub.
Thaum twg thiab Yuav Siv Li Cas Clomid
Clomid tuaj hauv 50- milligram ntsiav tshuaj. Qhov pib koob tshuaj ntau tshaj plaws yog ib ntsiav tshuaj ib hnub rau tsib hnub, pib rau hnub thib peb, plaub lossis hnub thib tsib ntawm koj lub cev xeeb tub. Los ntawm qhov ntawd (tshwj tsis yog tias koj siv Clomid nrog lub voj voog IUI lossis IVF), koj yuav tsum muaj kev sib deev raws sijhawm rau koj lub qhov rais fertile, uas yog lub sijhawm rau-lossis-hnub lub sijhawm thaum koj coj khaub ncaws uas koj muaj peev xwm ua tau. cev xeeb tub.
Yog tias koj tsis xeeb tub thaum koj thawj lub hlis ntawm kev noj Clomid, koj tus kws kho mob tuaj yeem nce koj cov koob tshuaj rau ob lossis peb ntsiav tshuaj ib hnub twg thaum koj lub voj voog tom ntej. Tsis txhob noj Clomid yam tsis muaj tshuaj.
Yuav noj npaum li cas
Cov koob tshuaj pom zoo rau thawj chav kawm ntawm Clomid yog ib ntsiav tshuaj ib hnub rau tsib hnub thaum pib ntawm koj lub voj voog. Yog tias ovulation tsis tshwm sim, koj tus kws kho mob yuav qhia koj kom nce koob tshuaj Clomid hauv kev kho mob tom ntej.
Tsis txhob noj tshuaj ntau ntxiv tshwj tsis yog koj tus kws kho mob qhia kom ua li ntawd.
Kev noj ntau tshaj li qhov koj tus kws kho mob tau sau tseg tuaj yeem ua rau koj lub zes qe menyuam, ua rau koj lub zes qe menyuam puas tsuaj thiab ua rau koj noj qab haus huv.
Cov ntaub ntawv kho mob
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Cov npe lag luam |
Clomiphene, Clomiphene, Clomid |
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CAS |
911-45-5 |
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Molar loj |
405.966 |
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MF |
C26H28ClNO |
|
Purity |
Tshaj 98% |
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Yam khoom |
50 mg x 100 |
Txhua yam kev xav tau, thov hu rau peb
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Clomid ua dab tsi?
Clomid, los yog clomiphene citrate, yog ib qho tshuaj uas ua haujlwm los ntawm kev cuam tshuam cov tshuaj hormones hauv lub cev los txhawb cov poj niam ovulation. Nws feem ntau yog siv los kho kev xeeb tub los ntawm inducing tso tawm cov tshuaj hormones xav tau rau ovulation tshwm sim.
Nov yog cov ncauj lus kom ntxaws ntxiv ntawm Clomid ua haujlwm li cas:
Hormonal Stimulation:Clomid cuam tshuam nrog hypothalamus hauv lub hlwb, txhawb kev tso tawm ntawm Gonadotropin-Releasing Hormone (GnRH).
Pituitary Stimulation:GnRH ua rau lub caj pas pituitary tsim ntau cov tshuaj Follicle-Stimulating Hormone (FSH) thiab Luteinizing Hormone (LH) ntau dua li niaj zaus.
Ovarian teb:Cov qib FSH nce ntxiv txhawb lub zes qe menyuam kom loj hlob thiab loj hlob follicles, uas yog cov kua dej puv lub hnab uas cov qe loj hlob tuaj.
Ovulation:Qhov nce hauv LH ua rau qhov kawg maturation thiab tso tawm ntawm lub qe los ntawm cov follicle tseem ceeb. Cov txheej txheem no yog ovulation, uas ua rau kom muaj feem ntawm fertilization.
Qhov tseem ceeb, Clomid ua raws li kev pab cuam fertility los ntawm kev cuam tshuam cov hormonal signals uas tswj kev coj khaub ncaws, txhawb kev loj hlob thiab tso tawm ntawm cov qe loj.
Nws yog ib qho tseem ceeb uas yuav tsum nco ntsoov tias Clomid yuav tsum tsuas yog siv nyob rau hauv kev saib xyuas ntawm tus kws kho mob, vim nws cov koob tshuaj thiab kev tswj hwm yuav tsum tau ua tib zoo saib xyuas kom ua kom nws cov txiaj ntsig zoo thaum txo qis cov kev mob tshwm sim.
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