BNP 2,4-DNP For Bodybuilding CAS:119-26-6

    2, 4-DNP yog dab tsi?

2,4-DNP (2,4-Dinitrophenol) yog cov organic compound nrog cov tshuaj formula C6H4N2O5. Cov molecule yog tus cwj pwm los ntawm kev muaj ob pawg nitro (-NO2) txuas rau lub nplhaib benzene, tshwj xeeb ntawm 2nd thiab 4 txoj haujlwm, yog li lub npe "2,4-dinitrophenol." Nws yog xim daj, crystalline khoom uas tau siv rau ntau yam kev lag luam, xws li hauv kev tsim cov dyes, explosives, thiab tshuaj tua kab. Txawm li cas los xij, nws daim ntawv thov tsis zoo tshaj plaws yog ua tus neeg sawv cev poob qis vim nws muaj peev xwm ua kom metabolic tus nqi los ntawm uncoupling oxidative phosphorylation hauv mitochondria.

2, 4-DNP yog ib qho yooj yim organic molecule tab sis nrog ib tug heev reactive thiab tshuaj lom. Nov yog nws cov khoom siv tshuaj lom neeg tseem ceeb:

1.Molecular Formula: C6H4N2O5

2.Molar MassYog ': 184.11 g/mol

3. Kev tshwm sim: Yellow crystalline khoom

4. Melting PointKub: 112 degree (233.6 degree F)

5. Boiling Point: Decomposes ua ntej boiling

6. Solubility: me ntsis soluble hauv dej, soluble heev hauv cov kuab tshuaj organic xws li ethanol, acetone, thiab benzene

7.Reactivity: Cov tshuaj muaj zog heev vim muaj cov pab pawg nitro, uas ua rau nws muaj zog oxidizing tus neeg sawv cev thiab tshuaj lom neeg.

8.p qha: Kwv yees li 4.1, qhia tias nws yog cov kua qaub tsis muaj zog

Lub luag haujlwm tseem ceeb ntawm kev ua haujlwm rau 2,4-DNP yog nyob rau hauv nws lub peev xwm los uncouple oxidative phosphorylation hauv mitochondria, uas yog cov txheej txheem tseem ceeb hauv kev tsim hluav taws xob. Raws li ib txwm muaj, mitochondria hauv hlwb tsim lub zog hauv daim ntawv ntawm adenosine triphosphate (ATP) los ntawm cov txheej txheem hu ua oxidative phosphorylation. Cov txheej txheem no suav nrog kev hloov pauv ntawm cov hluav taws xob los ntawm cov txheej txheem ntawm cov protein ntau hauv cov mitochondrial membrane, thaum kawg ua rau cov synthesis ntawm ATP.

2; Qhov "uncoupling" nyhuv no ua rau mitochondria noj ntau lub zog (hauv daim ntawv ntawm cov rog thiab carbohydrates) kom tswj tau cov proton gradient, ua rau muaj kev nce hauv metabolic tus nqi thiab kub ntau lawm. Qhov tseem ceeb, lub cev hlawv ntau calorie ntau ntau yam tsis tau tsim lub zog ntxiv, uas tuaj yeem ua rau poob phaus.

1. Kev lag luam siv:

● Dyes: 2,4-DNP tau siv rau hauv kev tsim cov azo dyes, uas paub txog lawv cov xim vibrant.

● Cov khoom tawg: Vim nws cov khoom oxidizing, 2,4-DNP tau raug siv los tsim cov khoom tawg.

● Tshuaj tua kab: Nws kuj tau siv los ua tshuaj tua kab vim nws muaj tshuaj lom rau kab thiab lwm yam kab tsuag.

2. Nyhav Poob:

● Keeb Kwm Siv: Hauv xyoo 1930, 2,4-DNP tau ua lag luam raws li cov tshuaj poob phaus. Nws lub peev xwm los nce metabolic tus nqi ua rau nws ua tau zoo rau kev poob phaus sai. Txawm li cas los xij, nws raug txiav tawm vim muaj kev phiv loj heev, suav nrog hyperthermia, cataracts, thiab tuag.

● Tsis raug cai siv: Txawm tias raug txwv, 2,4-DNP tseem siv los ntawm qee tus kws tsim lub cev thiab cov tib neeg nrhiav kev poob phaus sai. Nws yog ib qho tseem ceeb uas yuav tsum nco ntsoov tias kev siv 2,4-DNP rau kev poob phaus yog qhov txhaum cai hauv ntau lub tebchaws thiab ua rau muaj kev pheej hmoo loj rau kev noj qab haus huv.

Cov txiaj ntsig:

1. Ceev ceev poob: Qhov txiaj ntsig tseem ceeb ntawm 2,4-DNP yog nws lub peev xwm los ua kom poob phaus sai. Los ntawm uncoupling oxidative phosphorylation, nws nce metabolic tus nqi thiab calorie kev siv nyiaj.

2.Fat Poob: Cov khoom sib xyaw tshwj xeeb yog tsom rau cov khw muag khoom rog, ua rau txo qis hauv lub cev rog feem pua.

Kev pheej hmoo:

1.Hyperthermia: Ib qho kev phom sij txaus ntshai tshaj plaws ntawm 2,4-DNP yog hyperthermia, uas tuaj yeem ua rau lub cev tsis ua haujlwm thiab tuag. Qhov nce metabolic tus nqi ua rau muaj cua sov ntau dhau, uas tuaj yeem ua rau lub cev muaj peev xwm tswj tau qhov kub thiab txias.

2. Tachycardia thiab Arrhythmias: 2,4-DNP tuaj yeem ua rau lub plawv dhia thiab lub plawv dhia tsis zoo, uas tuaj yeem ua rau muaj kev phom sij rau lub neej.

3. Ua pa nyuaj: Vim tias qhov kev xav tau ntawm cov metabolism ntau ntxiv, lub cev yuav xav tau cov pa oxygen ntau dua, ua rau ua pa nyuaj.

Nws yog ib qho tseem ceeb kom nco ntsoov tias kev siv 2,4-DNP poob siab heev vim nws cov kev mob tshwm sim hnyav thiab muaj peev xwm ua rau tuag taus. Txawm li cas los xij, rau cov ntaub ntawv xov xwm, cov koob tshuaj keeb kwm tau tham hauv qab no.

Keeb kwm Dosage:

● Pib Dose: Hauv xyoo 1930, cov koob tshuaj pib ib txwm nyob ib ncig ntawm 2-3 mg / kg ntawm lub cev hnyav ib hnub.

● Siv Tau Zoo: Rau kev poob phaus, koob tshuaj feem ntau yog los ntawm 3-5 mg/kg ntawm lub cev hnyav ib hnub. Txawm li cas los xij, qhov koob tshuaj no ua rau muaj kev pheej hmoo loj.

● Tshuaj lom: Cov koob tshuaj ntau dua 5 mg / kg ib hnub yog suav tias yog tshuaj lom thiab tuaj yeem ua rau muaj kev phom sij rau lub neej.

Kev tswj hwm:

● Cov ntsiav tshuaj ntawm qhov ncauj: 2,4-DNP muaj keeb kwm muaj nyob rau hauv daim ntawv ntsiav tshuaj ntawm qhov ncauj. Cov ntsiav tshuaj tau noj txhua hnub, nrog kev saib xyuas kom zoo rau cov kev mob tshwm sim.

● Ceev faj: Vim nws qhov ntsuas qhov ntsuas nqaim (qhov ntau ntawm qhov koob tshuaj zoo thiab koob tshuaj lom), 2,4-DNP yuav tsum tau txhaj tshuaj meej heev. Kev noj tshuaj me me tuaj yeem ua rau mob hnyav lossis tuag taus.

Kev ncig:

● Absorption: 2,4-DNP yog nqus tau sai sai ntawm lub plab zom mov thaum noj qhov ncauj. Nws raug faib thoob plaws hauv lub cev, nrog rau kev nyiam rau adipose (rog) cov ntaub so ntswg vim nws lipophilic xwm.

●Metabolism: Cov compound yog metabolized nyob rau hauv daim siab, qhov uas nws undergoes txo nyob rau hauv tsim aminonitrophenols, uas yog ces conjugated thiab tawm hauv cov zis.

● Tshem tawm: Thawj txoj kev ntawm excretion yog los ntawm lub raum. Vim nws cov tshuaj lom neeg, lub cev sim tshem tawm 2,4-DNP kom sai li sai tau, tab sis cov txheej txheem tuaj yeem ua rau qeeb, ua rau raug mob ntev.

Ib nrab neej:

● Plasma Half-Life: Lub neej ib nrab ntawm 2,4-DNP hauv tib neeg lub cev yog qhov ntev, txij li 12 txog 24 teev, nyob ntawm seb tus neeg mob metabolic li cas.

● Lub Sij Hawm Ntev: Vim nws ntev ib nrab-lub neej thiab tsub zuj zuj nyob rau hauv cov ntaub so ntswg adipose, cov teebmeem ntawm 2, 4-DNP tuaj yeem ntev txawm tias tom qab txiav kev siv. Qhov no tuaj yeem ua rau qeeb toxicity, qhov twg cov tsos mob yuav tshwm sim tom qab noj cov tshuaj zaum kawg.

Hom	BNP
Cov npe lag luam	2,4-Dinitrophenol,2,4-DNPH,2,4-DNP,DNPH,Brady's reagent,Borche's reagent
CAS	119-26-6
Molar loj	184.107
MF	C6H4N2O5
Purity	Tshaj 98%
Yam khoom	200 mg x 50

 

 

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2,4-DNP yog cov tshuaj muaj zog thiab txaus ntshai heev nrog keeb kwm tsis sib haum xeeb. Thaum nws muaj txiaj ntsig zoo rau kev poob phaus sai, cov kev pheej hmoo cuam tshuam nrog nws siv deb tshaj qhov txiaj ntsig. Qhov muaj peev xwm ua rau muaj kev phom sij rau lub neej, suav nrog hyperthermia, tachycardia, ua pa nyuaj, thiab tuag, ua rau nws tsis tsim nyog thiab tsis raug cai rau kev poob phaus. Txawm hais tias nws cov ntawv thov kev lag luam, kev siv 2,4-DNP hauv tib neeg yog qhov txhaum cai thiab tsis ncaj ncees. Txhua tus neeg xav txog kev poob phaus yuav tsum nrhiav txoj hauv kev nyab xeeb thiab ruaj khov dua nyob rau hauv kev taw qhia ntawm tus kws kho mob.

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