Pregabalin yog cov tshuaj feem ntau siv los kho cov mob neuropathic (mob los ntawm kev puas tsuaj lossis kev ua haujlwm tsis zoo ntawm cov hlab ntsha) thiab raws li kev kho mob ntxiv rau qee hom qaug dab peg. Nws kuj tseem siv los tswj fibromyalgia, kev ntxhov siab dav dav (GAD), thiab lwm yam mob. Pregabalin belongs rau ib chav kawm ntawm cov tshuaj hu ua anticonvulsants lossis tshuaj antiepileptic. Nov yog li cas pregabalin cuam tshuam rau lub cev:
Modulation ntawm Neurotransmitter Tso Tawm: Pregabalin khi rau ib lub subunit ntawm voltage-gated calcium channel nyob rau hauv lub hauv paus paj hlwb (CNS). Los ntawm kev ua li ntawd, nws txo qis kev tso tawm ntawm cov neurotransmitters xws li glutamate, norepinephrine, thiab tshuaj P. Qhov kev hloov pauv ntawm cov tshuaj neurotransmitter tso tawm ua rau nws cov teebmeem analgesic (mob-relieving).
Txo qhov mob paj hlwb: Pregabalin yog tshwj xeeb tshaj yog zoo nyob rau hauv kev kho mob neuropathic mob los ntawm modulating cov kev ua ntawm overactive paj hlwb. Nws tuaj yeem pab txo qis qhov txawv txav ntawm cov hlab ntsha puas lossis ua haujlwm tsis zoo, yog li txo qhov mob cuam tshuam nrog cov mob xws li mob ntshav qab zib neuropathy, postherpetic neuralgia (shingles), thiab paj hlwb raug mob.
Cov teebmeem Anticonvulsant: Pregabalin muaj anticonvulsant zog, txhais tau tias nws tuaj yeem pab tswj kev ua haujlwm tsis zoo ntawm lub hlwb. Nws yog siv los ua ib qho kev kho mob rau kev qaug dab peg ib nrab ntawm cov neeg laus uas muaj mob qaug dab peg, pab txo qhov zaus thiab qhov hnyav ntawm qaug dab peg.
Cov teebmeem anxiolytic: Pregabalin kuj raug sau tseg rau kev kho mob ntawm kev ntxhov siab dav dav (GAD). Txawm hais tias qhov tseeb ntawm nws cov teebmeem anxiolytic tsis nkag siab tag nrho, nws ntseeg tau tias muaj kev hloov pauv ntawm cov neurotransmitter tso tawm hauv lub hlwb hauv cheeb tsam cuam tshuam nrog kev tswj hwm kev ntxhov siab, xws li amygdala.
Cov nqaij ntshiv: Pregabalin kuj tseem muaj cov leeg mob me me, ua rau nws muaj peev xwm txo tau qee yam mob, xws li mob musculoskeletal txuam nrog fibromyalgia.
