Letrozole yog cov tshuaj siv feem ntau hauv kev kho mob fertility, tshwj xeeb tshaj yog rau cov poj niam uas muaj teeb meem ovulation. Nws yog nyob rau hauv ib chav kawm ntawm cov tshuaj hu ua aromatase inhibitors thiab feem ntau yog siv off-label rau inducing ovulation.
Nov yog qhov nws ua haujlwm li cas: Letrozole inhibits kev tsim cov tshuaj estrogen los ntawm kev thaiv cov enzyme hu ua aromatase, uas hloov cov androgens rau hauv estrogen. Los ntawm kev txo cov tshuaj estrogen, nws tuaj yeem txhawb kev tso tawm ntawm follicle-stimulating hormone (FSH) los ntawm cov qog pituitary. Qhov no, nyob rau hauv lem, ua rau txoj kev loj hlob ntawm follicles nyob rau hauv lub zes qe menyuam, ua rau ovulation.
Hauv cov poj niam uas tsis muaj ovulation los yog tsis ovulate tag nrho (ib yam mob hu ua anovulation), Letrozole tuaj yeem pab txhawb ovulation, ua rau muaj feem ntau ntawm kev xeeb tub. Nws feem ntau tau sau tseg raws li kev kho mob thawj zaug rau cov xwm txheej zoo li polycystic zes qe menyuam syndrome (PCOS) qhov twg ovulation tsis sib xws.
Raws li nrog rau txhua yam tshuaj, nws tseem ceeb heev uas yuav tsum tau noj Letrozole nyob rau hauv kev saib xyuas ntawm tus kws kho mob uas tuaj yeem saib xyuas nws cov teebmeem thiab kho cov tshuaj raws li qhov xav tau los ua kom nws cov txiaj ntsig tau zoo thaum txo qis cov kev mob tshwm sim.
