Stanozolol uatsis ncaj qha nce ntau lawm lossis tso tawm ntawm tib neeg Kev Loj Hlob Hormone (hGH)los ntawm pituitary caj pas.
Txawm li cas los xij, nws cov teebmeem ntawm lub cev tuaj yeem cuam tshuam rauLoj hlob Hormone / IGF-1 axisnyob rau hauv ib txoj kev indirect thiab complex. Nov yog cov ncauj lus kom ntxaws:
1. Kev xav tsis thoob
Ntau tus neeg koom nrog anabolic steroids nrog kev loj hlob hormone vim tias ob qho tib si siv rau kev loj hlob ntawm cov leeg thiab kev ua tau zoo. Qhov no ua rau qhov kev xav tias steroids zoo li stanozolol yuav tsum nce qib hGH. Kev tshawb fawb, qhov no tsis yog thawj lossis ncaj qha mechanism.
2. Kev Sib Raug Zoo: IGF-1
● Stanozolol tuaj yeemnce kev ua haujlwm ntawm Insulin-zoo li Growth Factor-1 (IGF-1), uas yog lub ntsiab nruab nrab ntawm hGH cov teebmeem anabolic.
●hGH ua haujlwm feem ntau los ntawm kev txhawb lub siab los tsim IGF-1. Qee qhov kev tshawb fawb qhia tias qee yam anabolic steroids, suav nrog stanozolol, tuaj yeemtxhim kho qhov rhiab heev ntawm cov ntaub so ntswg rau IGF-1los yog cuam tshuam nws cov proteins uas khi, ua rau IGF-1 uas twb muaj lawm zoo dua.
● Hauv cov ntsiab lus yooj yooj yim: Stanozolol tuaj yeem pab "xauv" cov leeg nqaij - txhim kho lub peev xwm ntawm GH / IGF-1 uas twb muaj lawm es tsis yog nce tus nqi hGH nws tus kheej.
3. Muaj peev xwm tiv thaiv
Tseem ceeb, zoo li tag nrho cov anabolic -androgenic steroids (AAS), stanozolol tuaj yeemcuam tshuam lub cev lub ntuj endocrine system:
●Nws tuaj yeem cuam tshuam cov tshuaj testosterone ntuj los ntawm kev tawm tswv yim tsis zoo ntawm hypothalamic -pituitary-gonadal (HPG) axis.
●Thaum nws ncaj qha cuam tshuam rau lub pituitary'ssomatotrophs(hGH- tsim cov hlwb) tsis tshua meej, kev tsim txom loj ntawm AAS tuaj yeem cuam tshuam qhov sib npaug ntawm cov tshuaj hormones pituitary thaum lub sijhawm.
4. Cov pov thawj qhia li cas
● Cov kev tshawb fawb thaum ntxov xyoo 1980s thiab 1990s qee zaum pom muaj qhov nce qis hauv hGH hauv qee cov neeg (xws li, hauv cov menyuam yaus uas muaj kev loj hlob tsis zoo lossis hauv qee tus neeg ncaws pob), tab sis cov kev tshawb pom no tsis sib haum thiab tsis tshwj xeeb rau stanozolol.
● Cov txiaj ntsig zoo sib xws thiab lees txais yog nyob rauIGF-1 kev ua haujlwm thiab khaws cia nitrogen, uas txhawb nqa lub xeev anabolic (cov leeg-tsim) lub xeev.
●Qhov loj hlob ntawm cov leeg pom nrog kev siv stanozolol feem ntau yog vim nwsncaj qha kev ua androgenic ntawm cov leeg hlwb receptorsthiab nws lub peev xwm muaj peev xwm ua kom cov protein synthesis thiab txo cortisol cov teebmeem catabolic.
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