MK-677, tseem hu ua Ibutamoren, yog ib qho kev loj hlob hormone secretagogue, lub ntsiab lus nws txhawb kev tso tawm ntawm kev loj hlob hormone. Muaj qee cov pov thawj qhia tias MK-677 tuaj yeem nce qib ntawm kev loj hlob hormone thiab insulin-zoo li kev loj hlob yam 1 (IGF-1), uas yog qhov tseem ceeb hauv kev loj hlob thiab kev loj hlob. Qhov no tau ua rau muaj kev cia siab thiab qee qhov kev lees paub tias nws yuav nce qhov siab, tshwj xeeb tshaj yog rau cov neeg hluas uas cov phiaj xwm loj hlob tseem tsis tau kaw.
Cov pov thawj scientific thiab qhov siab nce
● Kev loj hlob Prepubertal: Muaj qee cov pov thawj qhia tias MK-677 tuaj yeem ua rau muaj qhov siab ntawm cov menyuam prepubertal. Piv txwv li, kev tshawb fawb txog kev kho cov tshuaj hormones loj hlob, uas MK-677 mimics, tau pom cov txiaj ntsig zoo ntawm qhov siab hauv cov menyuam yaus uas muaj qhov tsis zoo ntawm cov tshuaj hormones.
●Postpubertal Loj hlob: Rau cov neeg laus lossis cov neeg postpubertal, qhov muaj peev xwm nce qhov siab yog tsawg heev. Thaum daim phiaj loj hlob (epiphyseal daim hlau) kaw tom qab puberty, ntev pob txha loj hlob (thiab yog li qhov siab nce) nres. MK-677 yuav tsis tuaj yeem rov qhib cov phiaj no, yog li nws tsis zoo li yuav nce qhov siab ntawm cov neeg laus.
Kev txiav txim siab thiab kev pheej hmoo
● Cov teebmeem: MK-677 tuaj yeem ua rau muaj kev phiv xws li qab los noj mov, edema (kwv yees), mob pob qij txha, thiab muaj peev xwm tiv thaiv insulin.
● Teeb meem kev cai lij choj thiab kev ncaj ncees: MK-677 tsis tau pom zoo los ntawm FDA rau qhov nce siab lossis kho qhov tsis zoo. Nws yog feem ntau siv nyob rau hauv kev tshawb fawb chaw, thiab nws siv sab nraud ntawm cov chaw no tsis zoo tswj.
Xaus
MK-677 tej zaum yuav muaj qee lub peev xwm rau qhov siab nce hauv cov menyuam yaus prepubertal, tab sis rau cov neeg laus, nws tsis zoo li yuav muaj kev cuam tshuam rau qhov siab vim yog kaw ntawm daim phiaj loj hlob. Yog tias xav txog MK-677 lossis ib qho kev kho mob ntsig txog kev loj hlob, nws yog ib qho tseem ceeb uas yuav tau sab laj nrog tus kws kho mob kom nkag siab txog cov txiaj ntsig thiab kev pheej hmoo, thiab kom ntseeg tau tias kev kho mob muaj kev nyab xeeb thiab tsim nyog rau tus neeg mob tshwj xeeb.
