Tirzepatide (Mounjaro / Zepbound) yog GIP / GLP-1 receptor agonist. Nws ua haujlwm los ntawm kev txo qis qab los noj mov, ua kom lub plab zom mov qeeb, thiab txhim kho cov tshuaj insulin. Cov tshuaj nws tus kheej tsis muaj cov txheej txheem uas tsom rau cov leeg nqaij kom puas tsuaj.
Txawm li cas los xij,ib yamtxoj kev poob phaus sai-txawm yog los ntawm kev phais bariatric, tsawg heev -calorie noj, los yog muaj zog qab los noj mov suppressants- ua rau poob ntawmlean body mass (muscle)nrog rog. Qhov no yog physiological kev muaj tiag.
Thaum koj poob phaus sai:
● Caloric Deficit:Lub cev zom cov nqaij ntshiv rau lub zog (gluconeogenesis) yog tias nws hnov qab tshaib plab.
● Kev noj cov protein ntau:Kev qab los noj mov feem ntau ua rau nws nyuaj rau noj cov protein txaus, uas yog qhov tseem ceeb rau kev tswj cov leeg nqaij.
● Hormonal Signals:Kev hloov pauv loj heev hauv kev muaj zog ua rau lub cev poob qis "kim" cov nqaij mos (cov leeg) kom txuag tau lub zog.
2. Cov ntaub ntawv: Cov leeg poob ntau npaum li cas?
Cov ntaub ntawv soj ntsuam kuaj mob rau tirzepatide (cov kev tshawb fawb SURMOUNT) qhia tau tias20% mus rau 40% ntawm tag nrho qhov hnyav poobtuaj yeem los ntawm lean loj (cov leeg nqaij), nyob ntawm qhov kev tshawb fawb thiab cov pej xeem ntawm cov neeg mob.
Txhawm rau muab qhov no rau hauv kev pom:
● Hauv cov tshuaj, kev poob phaus tsis muaj kev tawm dag zog feem ntau ua rau20–30%ntawm qhov hnyav poob yog cov leeg.
● Nrog tirzepatide, vim tias qhov poob phaus feem ntau tshwm sim ntau dua (15-22% ntawm tag nrho lub cev qhov hnyav), qhov kawg ntawm cov leeg nqaij poob tuaj yeem yog qhov tseem ceeb.
● Piv txwv li, yog tias ib tug neeg poob 50 lbs (22.7 kg), lawv yuav poob 10 mus rau 15 lbs ntawm cov leeg nqaij yog tias lawv tsis cuam tshuam.
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